* The product images are for reference only. Generic equivalents may also be supplied by alternate manufacturers.
How and Where to Buy Estrace Online?
You can buy Estrace online through our Canadian International Pharmacy at huge savings. We offer RX and OTC medications online with a valid prescription from your doctor. At Canadian Pharmacy World, your health is our priority. You can place the order online, by mail, by fax or toll-free over the telephone at 1866-485-7979.
Are There Alternative Names for the Brand and Generic Estrace?
The Estrace Vaginal Cream comes from United States and is manufactured by Actavis. The brand Estrace tablets come from Canada manufactured by Acerus Pharma and from India by a different manufacturer. The generic equivalent of Estrace is estradiol and it comes from Canada also called Lupin Estradiol manufactured by Lupin.
What Dosages and Forms is Estrace available in?
Estrace is available in dosage forms of 0.5 mg, 1 mg and 2 mg in the bottles of 100 tablets. The generic form of Estrace (estradiol) is available in the dosage forms of 0.5 mg, 1 mg and 2 mg in the packaging of 100 tablets.
What is Estrace used for?
Estrace is indicated for the treatment of menopause symptoms (moderate to severe hot flashes). This medication is also used for the treatment of moderate to severe dryness, itching, burning and itching around the vagina, which occurs due to estrogen deficiency and for the prevention of the development of osteoporosis (thinning of bones that makes them weaker and easier to break) when combined with other important therapeutics such as diet, calcium and vitamin D intake, smoking cessation, and regular physical weight-bearing exercises. Estrace contains 17ß-estradiol and works by replacing the diminished estrogen production by the body. Estrogens are female hormones that are produced by the body and are required for the normal sexual development and regulation of menstrual periods during the childbearing years. Low estrogen levels during menopause can lead to osteoporosis (thinning of bones) and postmenopausal symptoms. Estrace helps to relieve postmenopausal symptoms and prevent osteoporosis. Estrace should be used only under the supervision of a doctor, with regular follow-up at least once a year to identify possible side effects associated with its use. Your first follow-up visit should be within 3 to 6 months of the start of treatment. Your visit may include a blood pressure check, a breast exam, a Pap smear and pelvic exam. You should have a mammogram before starting treatment and at regular intervals as recommended by your doctor. if you still have a uterus, talk to your doctor about the addition of a progestin (another female hormone) to your therapy in order to prevent cancer of the uterus.
What Are The Possible Side Effects of Estrace?
Some of the common side effects of Estrace include breast pain and swelling, breast tenderness, irregular vaginal bleeding or spotting, vaginal itching/discharge or pain, depression, nervousness, irritability, allergic reaction and rash, hair loss or abnormal hair growth, increased blood sugar levels, change in blood pressure, change in weight, acne, change in cholesterol or triglyceride levels, stomach cramps, bloating, headache, dizziness, abdominal pain, nausea and vomiting. Many women, who take estrogens with a progestin will at the start have monthly vaginal bleeding, similar to menstrual periods again. This effect will continue for as long as the medicine is taken. Some uncommon side effects of Estrace include lumps or discharge from the breast, crushing chest pain or chest heaviness, pain in the groin, pain or swelling in the leg or feet, persistent sad mood, sharp pain in the chest, coughing blood or sudden shortness of breath, sudden partial or complete loss of vision, sudden loss of coordination, fainting, disturbance of speech or vision, weakness or numbness in an arm or leg, yellowing of skin, unexpected vaginal bleeding. These are not all the possible side effects of Estrace. In case of any unexpected effect, consult your healthcare professional immediately.
Are there any Precautions and Drug interactions for Estrace?
It is good to avoid alcohol while taking Estrace as acute alcohol intake while taking Estrace can lead to increased levels of circulating estradiol. Grapefruit Juice can increase the concentrations of estrogen in the body, resulting in side effects. Hence, drinking grapefruit juiced should be avoided while taking Estrace.
Do not take Estrace if you:
• Are pregnant or breastfeeding
• Have a liver disease
• Have or had a history of certain types of cancers such as cancer of the uterus
• Have or had a history of breast cancer
• Have been with endometrial hyperplasia (overgrowth of the lining of the uterus)
• Have experienced undiagnosed or abnormal vaginal bleeding
• Have a history of heart attack, heart disease, angina or stroke
• Have migraines
• Have a history of blood clot disorders including blood clots in the legs or lungs or active thrombophlebitis (blood clots and inflammation of veins)
• Are at high risk of developing blood clots if you were born with certain blood clotting disorders
• Have had partial or complete loss of vision due to a blood vessel disease of the eye
• Have had an allergic or unusual reaction to estrogen or any other component of Estrace tablets
Before taking Estrace, inform your doctor if you:
• Have a history of allergy or intolerance to any medicines or other substances
• Have a history of breast disease (such as breast lumps), breast biopsies or family history of breast cancer
• Have experienced any unusual or undiagnosed vaginal bleeding
• Have a history of uterine fibroids or endometriosis
• Have a history of liver disease, jaundice (yellowing of eyes or skin), or itching due to estrogen use or during pregnancy
• Have a history of a migraine headache
• Have a history of high blood pressure
• Have personal or family history of blood clots or a personal history of heart disease or stroke
• Are going to have surgery or need long bed rest
• Have or have had kidney disease, asthma or epilepsy
• Have a history of bone disease (metabolic conditions or cancers that can affect blood levels of calcium and phosphorus)
• Have been diagnosed with diabetes
• Have been diagnosed with porphyria (a disease of blood pigment)
• Have a history of high cholesterol or high levels of triglycerides
• Are pregnant or planning to become pregnant
• Are breastfeeding
• Have had a hysterectomy (surgical removal of the uterus)
• Smoke
• Have a history of depression.
Estrogens may raise the chance of uterine cancer. Estrogens should not be used to prevent heart disease or dementia. Estrogens with or without progestin should be used for the shortest time needed at the lowest useful dose.
Drug interactions
It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs. Some medications that can interact with Estrace include:
• Anticoagulants such as warfarin
• Antidiabetic agents such as metformin
• Medicines used for the treatment of heart diseases or high blood pressure such as diltiazem, verapamil
• Medicines used to prevent inflammation such as medicines containing phenylbutazone
• Medicines used to control epilepsy such as barbiturates, carbamazepine, primidone, phenytoin
• Medicines used to control anxiety such as meprobamate
• Medicines used to treat a bacterial infection such as rifampicin
• Grapefruit juice, and St. John's Wort
Estrace Storage and Safety Information
Estrace should be stored at room temperature between 15°C and 30°C, in a tightly closed container, protected from light. It should be kept out of sight and reach of children.
References:
1. http://s2.q4cdn.com/417379002/files/doc_downloads/products/ESTRACE-PM-(EN)-10-Aug-2015.pdf
* The product images are for reference only. Generic equivalents may also be supplied by alternate manufacturers.
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The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.
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